Ketoacidosis - A Complication of Atkins' Diet? The Real Story.

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  • matawguro
    Moderator
    • Jun 02, 2004
    • 950

    #1

    Ketoacidosis - A Complication of Atkins' Diet? The Real Story.

    For those who haven't heard, it's been all over the news that a 40-year old woman on Atkins was diagnosed as suffering from ketoacidosis. We already have at least to threads on the topic listed below:

    http://www.atkinsdietbulletinboard.c...ad.php?t=27200

    http://www.atkinsdietbulletinboard.c...ad.php?t=27198

    Rina Wilshire over at her Weight of the Evidence Blog managed to get ahold of the case details and comments on it.

    Note: Emphasis mine.

    That troubles me - we have thousands of participants from hundreds of studies to date and not one incident of ketoacidosis. Is it possible this woman's ketoacidosis was a result of her diet? I would say it's not impossible, but very highly improbable given the reams of data from clinical trials to date that have not found ketoacidosis as a complication, even in diabetic patients following a low-carb diet.

    The reason it isn't a complication is that dietary ketosis, in and of itself, does not cause ketoacidosis. More likely this woman experienced ketoacidosis as a result of something else and unfortunately her diet placed an obstacle in front of a complete investigation as to its cause.

    ...

    While this particular case study was interesting, it remains an "n of 1" since there are no other reports of this type of complication from any other clinician in the world, and the physician did not, in my opinion, explore all avenues for cause since he believed it could only be her diet - short-sighted and a headline grabber to be sure - good science, no.
    Some important points raised:


    • The woman was following the 1972 version of Atkins.
    • Her blood pH, blood glucose, and sodium was normal
    • She'd been vomiting for days
    • She had symptoms similar to methanol poisoning and was given treatment for such a condition.
    • The possibility of undiagnosed diabetes or cancer ws never explored.
    BTW, I have to add that Rina Wilshire's blog is recomended reading for anyone interested in the science behind low-carb lifestyles.
    Robbie T., 240/180/160. 41yr Male, Height 5'9"
    Started November 1, 2003. Minor goal (180lbs.) reached Oct. 30, 2004
    Lowest weight before slacking-off : 175lbs
    Quezon City, Philippines
    "Eppur si muove!"
  • Laurenfra
    *Administrator Emeritus*
    • Jun 17, 2004
    • 7431

    #2
    Re: Ketoacidosis - A Complication of Atkins' Diet? The Real Story.

    great post Robbie
    ~Lauren~



    support? Isn't it time to give some back?
    Ask a mod how today.

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    • big_bad_john
      ADBB Adventurer
      • Feb 12, 2006
      • 270

      #3
      Re: Ketoacidosis - A Complication of Atkins' Diet? The Real Story.

      I'm still busy ranting about capitalism....
      Big bad John, Leader amongst men and baker of cakes.

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      • staziaw
        • Jan 30, 2006
        • 2119

        #4
        Re: Ketoacidosis - A Complication of Atkins' Diet? The Real Story.

        Thanks for posting this! I saw the story on the Huffington Post and nearly had a coronary (completely un-Atkins-related! LOL). I was so hoppin' mad I actually had to post a comment on the article. Grrrr.

        At least we all know better!

        Big love!
        F/45(!?)/5'11"
        Highest Weight: 254
        Current Weight: 248 (7/30/09)
        Lowest Atkins Weight 196
        Desired Weight: unknown, but below 180
        1st Goal: 245

        Don't be afraid that your life will end,
        be afraid that it will never begin.
        sigpic
        Yes, these are wolves. Glorious wolves!

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        • not2late
          Moderator
          • May 09, 2003
          • 14677

          #5
          Re: Ketoacidosis - A Complication of Atkins' Diet? The Real Story.

          Originally posted by matawguro


          Some important points raised:

          • The woman was following the 1972 version of Atkins.
          • Her blood pH, blood glucose, and sodium was normal
          • She'd been vomiting for days
          • She had symptoms similar to methanol poisoning and was given treatment for such a condition.
          • The possibility of undiagnosed diabetes or cancer ws never explored.
          BTW, I have to add that Rina Wilshire's blog is recomended reading for anyone interested in the science behind low-carb lifestyles.
          I bolded the parts that is really interesting...By definition, ketoacidosis means the blood pH is low (not normal), the blood glucose is high (not normal) and the sodium is usually high due to dehydration. And since the woman was "vomitting for days", I would assume she had some degree of dehydration.

          Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes that mainly occurs in patients with type 1 diabetes, but it is not uncommon in some patients with type 2 diabetes. This condition is a complex disordered metabolic state characterized by hyperglycemia, ketoacidosis, and ketonuria.


          Here's a link that discusses ketosis and ketoacidosis.


          The other interesting thing is that she was treated for methanol poisoning. Methanol poisoning and ketoacidosis are two different things and are treated differently.

          Here's a link about methanol toxicity:
          Methanol, also known as wood alcohol, is a commonly used organic solvent that, because of its toxicity, can cause metabolic acidosis, neurologic sequelae, and even death, when ingested. It is a constituent of many commercially available industrial solvents and of poorly adulterated alcoholic beverages.


          Something else is most likely "up" with her. But the doctors will most likely write her case up in more detail and hopefully, we'll be able to see the specifics of the case are.
          ~Megs~
          242/141/160 (130)
          dress size 26/10/8
          5'4", Female, May 2, 2003
          My blog:
          http://mformiscellaneous.blogspot.com/

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