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Copyright 2006 Obesity & Diabetes Week via NewsRx.com & NewsRx.net
Obesity & Diabetes Week
October 23, 2006
SECTION: EXPANDED REPORTING; Pg. 73
LENGTH: 393 words
HEADLINE: DIET & NUTRITION;
Very low-carbohydrate diet improves gastroesophageal reflux and its symptoms in obese
BODY:
A very low-carbohydrate diet improves gastroesophageal reflux and its symptoms in obese.
According to a study from the United States, "Obese patients with gastroesophageal reflux disease (GERD) may experience resolution of symptoms utilizing a very low-carbohydrate diet. The mechanism of this improvement is unknown. This studied aimed to prospectively assess changes in distal esophageal acid exposure and GERD symptoms among obese adults initiating a very low-carbohydrate diet."
"We studied obese individuals with GERD initiating a diet containing less than 20 g/day of carbohydrates. Symptom severity was assessed using the GERD Symptom Assessment Scale-Distress Subscale (GSAS-ds). Participants underwent 24-hr esophageal pH probe testing and initiated the diet upon its completion. Within 6 days, a second pH probe test was performed. Outcomes included changes in the Johnson-DeMeester score, percentage total time with a pH <4 in the distal esophagus, and GSAS-ds scores. Eight participants were enrolled," described G.L. Austin and colleagues, University of North Carolina.
The results showed, "Mean Johnson-DeMeester score decreased from 34.7 to 14.0 (p=0.023). Percentage time with pH <4 decreased from 5.1% to 2.5% (p=0.022). Mean GSAS-ds score decreased from 1.28 to 0.72 (p=0.0004)."
The researchers concluded, "These data suggest that a very low-carbohydrate diet in obese individuals with GERD significantly reduces distal esophageal acid exposure and improves symptoms."
Austin and colleagues published their study in Digestive Diseases and Sciences (A very low-carbohydrate diet improves gastroesophageal reflux and its symptoms. Dig Dis Sci, 2006;51(
:1307-1312).
For more information, contact G.L. Austin, University of North Carolina, Division Gastroenterology & Hepatology, Bioinformat Bldg, CB 7080, Chapel Hill, NC, USA.
Publisher contact information for the journal Digestive Diseases and Sciences is: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands.
LowKeywords: Chapel Hill, North Carolina, United States, Diet and Nutrition, Digestive Disease, Esophageal, Gastroenterology, Gastroesophageal Reflux Disease, Gastrointestinal, Obesity, Very Low Carbohydrate Diet.
This article was prepared by Obesity & Diabetes Week editors from staff and other reports. Copyright 2006, Obesity & Diabetes Week via NewsRx.com.
LOAD-DATE: October 23, 2006
Obesity & Diabetes Week
October 23, 2006
SECTION: EXPANDED REPORTING; Pg. 73
LENGTH: 393 words
HEADLINE: DIET & NUTRITION;
Very low-carbohydrate diet improves gastroesophageal reflux and its symptoms in obese
BODY:
A very low-carbohydrate diet improves gastroesophageal reflux and its symptoms in obese.
According to a study from the United States, "Obese patients with gastroesophageal reflux disease (GERD) may experience resolution of symptoms utilizing a very low-carbohydrate diet. The mechanism of this improvement is unknown. This studied aimed to prospectively assess changes in distal esophageal acid exposure and GERD symptoms among obese adults initiating a very low-carbohydrate diet."
"We studied obese individuals with GERD initiating a diet containing less than 20 g/day of carbohydrates. Symptom severity was assessed using the GERD Symptom Assessment Scale-Distress Subscale (GSAS-ds). Participants underwent 24-hr esophageal pH probe testing and initiated the diet upon its completion. Within 6 days, a second pH probe test was performed. Outcomes included changes in the Johnson-DeMeester score, percentage total time with a pH <4 in the distal esophagus, and GSAS-ds scores. Eight participants were enrolled," described G.L. Austin and colleagues, University of North Carolina.
The results showed, "Mean Johnson-DeMeester score decreased from 34.7 to 14.0 (p=0.023). Percentage time with pH <4 decreased from 5.1% to 2.5% (p=0.022). Mean GSAS-ds score decreased from 1.28 to 0.72 (p=0.0004)."
The researchers concluded, "These data suggest that a very low-carbohydrate diet in obese individuals with GERD significantly reduces distal esophageal acid exposure and improves symptoms."
Austin and colleagues published their study in Digestive Diseases and Sciences (A very low-carbohydrate diet improves gastroesophageal reflux and its symptoms. Dig Dis Sci, 2006;51(
:1307-1312).For more information, contact G.L. Austin, University of North Carolina, Division Gastroenterology & Hepatology, Bioinformat Bldg, CB 7080, Chapel Hill, NC, USA.
Publisher contact information for the journal Digestive Diseases and Sciences is: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands.
LowKeywords: Chapel Hill, North Carolina, United States, Diet and Nutrition, Digestive Disease, Esophageal, Gastroenterology, Gastroesophageal Reflux Disease, Gastrointestinal, Obesity, Very Low Carbohydrate Diet.
This article was prepared by Obesity & Diabetes Week editors from staff and other reports. Copyright 2006, Obesity & Diabetes Week via NewsRx.com.
LOAD-DATE: October 23, 2006
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